Mastering TypeScript, Node.js, and Next.js as a full-stack developer:

1. Start with Foundations

2. Dive into TypeScript

3. Explore Node.js

4. Embrace Next.js for Frontend

5. Build Projects

6. Study Documentation and Tutorials

7. Take Online Courses

8. Engage in the Community

9. Read Books

10. Stay Updated

Remember, it's a journey, not a race. Seek help when stuck, and practice consistently to improve your skills. Happy coding!